# Random Walk with Restart Toolkit

## Apps

* [Find Functional Context using Lines of Evidence with RWRtools LOE](https://narrative.kbase.us/#catalog/apps/kb_djornl/run_rwr_loe/): uses Random Walk with Restart (RWR) to rank genes in the network starting from a Feature Set.
* [Find Gene Set Interconnectivity using Cross Validation with RWRtools CV](https://narrative.kbase.us/#catalog/apps/kb_djornl/run_rwr_cv): performs cross validation on a single gene set, finding the RWR rank of the left-out genes.

## Inputs

The input for this app is an annotated [Genome](/data/upload-download-guide/genome.md). 

The network data is maintained by KBase behind the scenes and can be found [here](https://github.com/kbaseapps/kb_djornl/blob/main/NETWORKS.md).

## Narratives

* [RWRtools Exascale and Petascale Network Analysis Demo Narrative](https://narrative.kbase.us/narrative/167526) – was created as part of the software publications for the RWRtoolkit (manuscript in preparation).
  * Created and made public by Kyle Sullivan of Oak Ridge National Laboratory
* [Microbial Genomics in KBase: Gene Feature Analysis](https://narrative.kbase.us/narrative/83681) – provides further examples of creating and working with FeatureSets derived from Genomes.

## Tutorial webinar

{% embed url="<https://www.youtube.com/watch?v=Dq5kZ_Sacy0>" %}
Tutorial webinar presented by Kyle Sullivan, Oak Ridge National Laboratory
{% endembed %}

## SFA Collaboration page

These apps were developed as part of the Exascale Network project led by Dan Jacobson. To learn more about this collaboration, see: <https://www.kbase.us/research/user-working-groups/#datascience>.


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